for Human Molecular Genetics Program (Ann and Robert H. Lurie Children's Hospital of Chicago Research Center)
Many of the most devastating and intractable diseases are caused by genetic defects. Errors or variations in single genes (monogenic diseases) or in multiple genes (polygenic diseases) can predispose to the disease process. The contribution of the Human Genome Project to our knowledge of gene sequences and structure has been immense. However, the availability of this tremendous knowledge base generates new challenges: to elucidate the function and regulation of genes, to establish how genetic errors cause disease, and most importantly, to translate these advances into innovative and effective therapies. The vision of the newly appointed leader of the Human Genetics Program, Ann Harris, Ph.D., formerly Professor of Paediatric Molecular Genetics at Oxford University, is to nurture a world class centre of translational genetic medicine.
Contact: Brian Corstange,
Web Site: http://www.childrensmrc.org/human_molecular_genetics