When   Thursday, September 24, 2009   Time   4:00 PM - 5:00 PM  
Where   Technological Instit M345 2145 Sheridan Rd.   map it
Audience   - Faculty/Staff - Student - Public
Contact   Virginia Lorenzo   847-491-5635  
Group   McCormick - Biomedical Engineering Department
More Info   http://www.bme.northwestern.edu

Shu Q. Liu, PhD
Biomedical Engineering Department, Northwestern University

ABSTRACT: Cardiomyocyte injury occurs in myocardial ischemia, resulting in impairment of cardiac function. As the endogenous protective function of adult cardiomyocytes is limited, nonmyocytic cells may be activated to protect myocardium from ischemic injury. We have recently discovered that the liver can respond to myocardial ischemia to upregulate secreted cardioprotective factors and mobilize its cells to ischemic myocardium, contributing to myocardial protection from ischemic injury. These naturally occurring mechanisms suggest a possibility of developing cardioprotective therapeutics based on myocardial ischemia-induced liver cell-secreted factors.