Northwestern Events Calendar

Feb
26
2015

BME Seminar Series: Steven George, MD, PhD

When: Thursday, February 26, 2015
4:00 PM - 5:00 PM CT

Where: Technological Institute, L361, 2145 Sheridan Road, Evanston, IL 60208 map it

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Professor Olds   (847) 467-2369

Group: McCormick - Biomedical Engineering Department (BME)

Category: Academic

Description:

Steven George, MD, PhD
Professor and Chair, Department of Biomedical Engineering
Washington University in St. Louis

Thursday, February 26th
4:00 – 5:00 PM, Tech L361
Reception to follow, 2nd floor Willens Wing Atrium

Title:
"Vascularizing Engineered (Cardiac and Tumor) Tissues In Vitro"

Abstract:
Tissue engineering holds enormous potential to not only replace or restore function to a wide range of tissues, but also to capture and control three-dimensional physiology in vitro (e.g., microphysiological systems). The latter has important applications in the fields of drug development, toxicity screening, modeling tumor metastasis, and repairing damaged cardiac (heart) muscle. In order to replicate the complex 3-D arrangement of cells and extracellular matrix (ECM), new human microphysiological systems must be developed, and must include a vascular supply. The vasculature not only provides the necessary convective transport of nutrients and waste in 3-D culture, it also couples and integrates the response of multiple organ systems. The past decade has brought tremendous advances in our understanding of new blood vessel formation, providing a rich environment to vascularize engineered tissues. Over the past four years we have developed a novel microfluidic-based system of 3-D human microtissues (~ 1 mm3) perfused with a network of human microvessels. This seminar will describe our approach and early results, including applications in tumor biology and cardiac tissue.

 

More Info Add to Calendar

Add Event To My Group:

Please sign-in