When:
Wednesday, September 16, 2015
12:00 PM - 1:00 PM CT
Where: Ward Building, 5-230, 303 E. Chicago Avenue, Chicago, IL 60611 map it
Audience: Faculty/Staff - Student - Public - Post Docs/Docs - Graduate Students
Contact:
Liz Barrera
(312) 503-4892
Group: Department of Pharmacology Seminars
Category: Lectures & Meetings
The Department of Pharmacology is pleased to welcome Dr. James S. Trimmer, Ph.D., Department of Neurobiology, Physiology & Behavior, University of California, Davis.
The following is an overview of this seminar, as described by Dr. Trimmer:
Ion channels are a diverse family of membrane proteins whose structural and functional diversity is tremendously enhanced by a variety of posttranslational regulatory events. I will discuss our efforts in proteomic level analyses of neuronal ion channels, and their expression and regulation, including generating and validating affinity reagents needed for such proteomic level analyses. These studies include mass spectrometric analyses of posttranslational modifications, the application of phosphospecific antibodies for analyses of dynamic regulation of ion channels, and multiplexed proteomic imaging, which together have allowed for novel insights into neuronal ion channels and their regulation.