When:
Tuesday, October 2, 2018
12:00 PM - 1:00 PM CT
Where: Robert H Lurie Medical Research Center, Baldwin Auditorium, 303 E. Superior, Chicago, IL 60611 map it
Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students
Contact:
Dr. Derek Walsh
(312) 503-4292
Group: Department of Microbiology-Immunology Seminars/Events
Category: Lectures & Meetings
Title:
“Cytokinin Signaling in Mycobacterium tuberculosis: Functions and Consequences"
K. Heran Darwin, PhD - New York University
Host: Derek Walsh PhD
Description:
Tuberculosis (TB) kills about 1.5 million people globally every year, making it the leading causes of death by an infectious agent. My lab is working to understand how Mycobacterium tuberculosis (Mtb) persists in animals by characterizing substrates of the Mtb proteasome. We reported the identification of a proteasome substrate called “lonely guy” (Log) that catalyzes the synthesis of cytokinins, which had previously only been characterized as plant hormones. In my talk I will discuss the function of cytokinins in Mtb as well as discuss the consequences of making too many cytokinins, which may provide a new understanding of host-pathogen interactions.