Northwestern University

Feb
21
Tue 12:00 PM

Structures and Functions of the Clostridium difficile Toxins, TcdA and TcdB: D. Borden Lacy, PhD

When: Tuesday, February 21, 2017
12:00 PM - 1:00 PM  

Where: Robert H Lurie Medical Research Center, BAldwin Auditorium, 303 E. Superior, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Dr. Karla Satchell   (312) 503-2162

Group: Microbiology-Immunology Seminars

Category: Lectures & Meetings

Description:

Microbiology-Immunology Seminar Series

Clostridium difficile infection (CDI) is the primary cause of hospital-acquired diarrhea and pseudomembranous colitis. Disease is associated with the activity of two toxins, TcdA and TcdB, which cause diarrhea, inflammation, and necrosis within the colon. The toxins are considered to be key antigens in vaccine development strategies and important targets for novel therapeutic discovery. This talk will discuss our recent progress in determining the structures and mechanisms of how these toxins disrupt host cell function.

D. Borden Lacy, PhD

Vanderbilt University

Host: Dr. Karla Satchell

 

 

 

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