When:
Tuesday, February 21, 2017
12:00 PM - 1:00 PM CT
Where: Robert H Lurie Medical Research Center, BAldwin Auditorium, 303 E. Superior, Chicago, IL 60611 map it
Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students
Contact:
Dr. Karla Satchell
(312) 503-2162
Group: Department of Microbiology-Immunology Seminars/Events
Category: Lectures & Meetings
Microbiology-Immunology Seminar Series
Clostridium difficile infection (CDI) is the primary cause of hospital-acquired diarrhea and pseudomembranous colitis. Disease is associated with the activity of two toxins, TcdA and TcdB, which cause diarrhea, inflammation, and necrosis within the colon. The toxins are considered to be key antigens in vaccine development strategies and important targets for novel therapeutic discovery. This talk will discuss our recent progress in determining the structures and mechanisms of how these toxins disrupt host cell function.
D. Borden Lacy, PhD
Vanderbilt University
Host: Dr. Karla Satchell