Northwestern University

Tue 12:00 PM

Microbiology-Immunology Department: Owen Pornillos, PhD

When: Tuesday, March 6, 2018
12:00 PM - 1:00 PM  

Where: Robert H Lurie Medical Research Center, Baldwin Auditorium, 303 E. Superior, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Dr. Mojgan Naghavi   312.503.4294

Group: Department of Microbiology-Immunology Seminars/Events

Category: Lectures & Meetings

More Info


The Department of Microbiology-Immunology Seminar Series

“Structural biology of HIV-1 Assembly and Maturation”

Owen Pornillos, PhD /University of Virginia


HIV assembly and maturation proceed through the programmed operation of molecular switches, which trigger both local and global structural rearrangements to produce infectious particles. Our group applies structural biology techniques to understand how the viral capsid initially assembles as a spherical, immature shell and then upon proteolysis re-assembles into a mature, fullerene capsid. We also help to elucidate the mechanisms of action of various experimental inhibitors of HIV assembly and maturation.

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