Northwestern University

Nov
29
Thu 4:00 PM

Microbiology-Immunology Department: Michael Lagunoff, PhD

When: Thursday, November 29, 2018
4:00 PM - 5:00 PM  

Where: Ward Building, 5-230, 303 E. Chicago Avenue, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Dr. Laimonis Laimins   312.503.0648

Group: Department of Microbiology-Immunology Seminars/Events

Co-Sponsor(s):
Virology Club

Category: Lectures & Meetings

Description:

 

Special Microbiology-Immunology and Virology Club Seminar

Title: "Metabolic Requirements for KSHV Latency”

 Michael Lagunoff Ph.D., Professor of Microbiology, University of Washington

Host: Laimonis Laimins, PhD

Summary:

 

The Lagunoff lab has found that Kaposi’s Sarcoma-herpesvirus latent infection dramatically alters the metabolic profile of infected endothelial cells, including inducing the Warburg effect (aerobic glycolysis), glutaminolysis and fatty acid synthesis. Importantly, they have found that many metabolic changes are required for the survival of latently infected cells. Recent work using more global screens has identified additional metabolic pathways required for latency that can be targeted by specific drugs.

 

 

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