When:
Wednesday, October 24, 2018
3:00 PM - 4:30 PM CT
Where: Robert H Lurie Medical Research Center, Baldwin Auditorium, 303 E. Superior, Chicago, IL 60611 map it
Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students
Contact:
Alexandra Kolot
(312) 503-6708
Group: Simpson Querrey Institute for BioNanotechnology (SQI)
Category: Lectures & Meetings
The Simpson Querrey Institute is pleased to announce the upcoming
Rising Stars of SQI Lecture
sponsored by the Peptide Synthesis Core and ANTEC
featuring
Sean Allen
PhD Candidate, The Evan Scott Lab
who will present a lecture titled
“Rapid, Sterile, and Clinical-Scale Synthesis and Directed Self-Assembly of Block Copolymers for Applications in Nanomedicine”
Wednesday, October 24, 2018
3:00-4:30 pm
Baldwin Auditorium
303 East Superior Street
Chicago Campus
Abstract: Polymeric nanocarriers can be engineered to deliver small molecule drugs, peptides, proteins, and nucleic acids in a targeted fashion for biomedical applications. Despite significant potential, nanomedicine remains sparsely adopted in clinical settings. One barrier to translation has been the transition from laboratory-scale to clinical-scale synthesis and preparation of nanocarriers. Our lab has focused on both the development and application of novel drug delivery systems as well as the rapid and sterile production of large uniform batches of nanocarriers for eventual clinical use. This process, flash nanoprecipitation, has allowed us to rapidly and reproducibly produce monodisperse gram-scale nanocarrier formulations for exploring toxicity and biodistribution in both murine and non-human primate models. I will present our recent applications of flash nanoprecipitation in nanomedicine, along with our new platforms for sustained drug release, treatment of atherosclerosis and glaucoma, and subunit vaccination.
Bio: Sean Allen received his B.A. from UC Berkeley and his M.S. from San Francisco State, both in Molecular and Cell Biology, prior to joining the IBiS program and the Scott Lab at Northwestern University for his PhD in 2013. He is entering his 6th year in the program, and plans to graduate at the end of 2018. He has published 7 original research articles and 2 review articles since joining the Scott Lab, and completed an internship at Genentech as an NIH Biotechnology Training Program grant recipient.