Northwestern University

Mon 4:00 PM

Using iPSCs to Study the Development and Function of Human Motor Neurons in Health and Disease

When: Monday, December 10, 2018
4:00 PM - 5:00 PM  

Where: Ward Building, 5-230, 303 E. Chicago Avenue, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Public - Post Docs/Docs - Graduate Students

Contact: Liz Murphy   312.503.4892

Group: Department of Pharmacology Seminars

Category: Lectures & Meetings


The Department of Pharmacology welcomes Evangelos Kiskinis, Ph.D., Assistant Professor, Department of Neurology, Northwestern University.

Our laboratory seeks to harness the power of pluripotent stem cells to understand how neuronal function is impaired in neurological disease. We utilize patient-specific induced pluripotent stem cells (iPSCs) and direct reprogramming methods to generate different neuronal subtypes of the central nervous system. We study these cells by using a combination of molecular, biochemical and functional electrophysiological assays. During this talk I will focus on our efforts to uncover the degenerative mechanisms that give rise to amyotrophic lateral sclerosis ALS, a devastating and untreatable disease that targets motor neurons.

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