Northwestern University

Dec
10
Mon 4:00 PM

Using iPSCs to Study the Development and Function of Human Motor Neurons in Health and Disease

When: Monday, December 10, 2018
4:00 PM - 5:00 PM  

Where: Ward Building, 5-230, 303 E. Chicago Avenue, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Public - Post Docs/Docs - Graduate Students

Contact: Liz Murphy   312.503.4892

Group: Department of Pharmacology Seminars

Category: Lectures & Meetings

Description:

The Department of Pharmacology welcomes Evangelos Kiskinis, Ph.D., Assistant Professor, Department of Neurology, Northwestern University.

Abstract:
Our laboratory seeks to harness the power of pluripotent stem cells to understand how neuronal function is impaired in neurological disease. We utilize patient-specific induced pluripotent stem cells (iPSCs) and direct reprogramming methods to generate different neuronal subtypes of the central nervous system. We study these cells by using a combination of molecular, biochemical and functional electrophysiological assays. During this talk I will focus on our efforts to uncover the degenerative mechanisms that give rise to amyotrophic lateral sclerosis ALS, a devastating and untreatable disease that targets motor neurons.

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