Northwestern University

Mon 12:00 PM

Dr. David Ripley: Endocrinopathy following traumatic brain injury: relationship to functional outcomes

When: Monday, February 11, 2019
12:00 PM - 1:00 PM  

Where: Shirley Ryan AbilityLab, 10th floor Conference A-B, 355 E. Erie, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Public - Post Docs/Docs - Graduate Students

Cost: None

Contact: Andrea Domenighetti, PhD   312.238.1030

Group: Shirley Ryan AbilityLab Research Seminar Series

Category: Lectures & Meetings

More Info



Neuroendocrine dysfunction following TBI was recognized as early as 1918 but remains under-diagnosed and under-treated. Symptoms of endocrine dysfunction such as deconditioning, fatigue, altered nutritional status, and weight loss, may interfere with the normal rehabilitation process. Single or multiple pituitary-target hormone disruption have been reported in 25-69% of patients in cross sectional studies. The most common hormonal deficits are in the hypothalamic-pituitary-gonadal (HPG) and growth hormone axes. Longitudinal studies of patients in the post-acute phase of TBI have documented pituitary dysfunction up to 3 years after injury. This presentation will present theories of the pathophysiology behind hormonal deficits following TBI, and work done on investigating the effects of hormonal deficits on functional status following TBI.

Speaker Info:

David Ripley, MD, MS, CRC, FAAPM&R is the Section Chief of Brain Injury Medicine and Rehabilitation and Medical Director of Workers Compensation Physician Practice at the Shirley Ryan AbilityLab (formerly, Rehabilitation Institute of Chicago). Dr. Ripley is board certified in Physical Medicine & Rehabilitation and Brain Injury Medicine. He holds an academic appointment as Associate Professor in the Department of PM&R at Northwestern University’s Feinberg School of Medicine, and is Program Director for the James and Carmelita O’Boyle Fellowship in Brain Injury Medicine. Prior to joining the faculty and staff at NUFMS and Shirley Ryan AbilityLab he served as Medical Director for the Rocky Mountain Regional Brain Injury Model System of Care for the 2007-2012 TBI Model Systems. Dr. Ripley’s clinical work involves the inpatient and outpatient management of patients with traumatic brain injury throughout the continuum of their recovery, beginning with acute care consultation in the ICU, through community reintegration to return to work or school as appropriate.

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