When:
Thursday, December 3, 2020
2:00 PM - 3:30 PM CT
Where: Online
Audience: Faculty/Staff - Student - Public - Post Docs/Docs - Graduate Students
Contact:
Yas Shemirani
Group: Physics and Astronomy Complex Systems Seminars
Category: Academic
Abstract:
We coexist with a vast number of microbes that live in and on our bodies. Those microbes and their genes are collectively known as the human microbiome, which plays important roles in human physiology and diseases. Many scientific advances have been made through the work of large-scale, consortium-driven metagenomic projects, which help us acquire more accurate organismal compositions and metabolic functions of the human microbiome. Yet, there are still many fundamental questions to be addressed at the systems level. In this talk, I will present our recent theoretical progress on understanding this complex ecosystem from community ecology, dynamical systems, and network science perspectives [1-5].
References:
[1] Bashan, Gibson, Friedman, Carey, Weiss, Hohmann, Liu. Universality of Human Microbial Dynamics. Nature 2016;534:259-262.
[2] Xiao, Angulo, Friedman, Waldor, Weiss, Liu. Mapping the ecological networks of microbial communities. Nature Communications 2017;8:2042.
[3] Angulo, Moog, Liu. A theoretical framework for controlling complex microbial communities. Nature Communications 2019;10:1045.
[4] Xiao, Angulo, Lao, Weiss, Liu. An Ecological Framework to Understand the Efficacy of Fecal Microbiota Transplantation. Nature Communications 2020;11:3329.
[5] Tian, Wang, Wu, Fan, Friedman, Dahlin, Waldor, Weinstock, Weiss, Liu. Deciphering Functional Redundancy in the Human Microbiome. Nature Communications (In Press)
Dr. Yang-Yu Liu, Harvard Medical School, Associate Scientist, Brigham and Women’s Hospital
Host: István Kovács
Keywords: Physics, Astronomy, Complex Systems