When:
Tuesday, October 26, 2021
11:00 AM - 12:00 PM CT
Where: Online
Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students
Cost: free
Contact:
Jodi Johnson
Group: Lurie Cancer Center Basic Science Programs
Category: Lectures & Meetings
The Lurie Cancer Center Basic Research Seminar Series and the Signal Transduction and Cancer Training Program (T32 CA070085) present:
Not All T Cell Responses are Created Equal
Stefani Spranger, PhD
Howard S, and Linda B. Stern
Career Development Professor Koch Institute for Integrative
Assistant Professor of Biology, MIT
Tuesday, October 26, 2021
11:00 a.m. - 12:00 p.m.
Cancer immunotherapies have revolutionized cancer treatment, but only a fraction of patients respond. The presence of CD8 cytolytic, "killer" T cells within the tumor microenvironment is a key factor in response to checkpoint blockade therapy. This talk will highlight factors that contribute to T cell exclusion from the tumor microenvironment, including tumor cell-intrinsic, tissue-macroenvironmental or environmental factors (e.g. infections). The Spranger lab studies lung and pancreatic cancer as respective models of immunotherapy sensitive and resistant cancer types.
All members of the Northwestern Medicine community are invited to attend.