Northwestern Events Calendar

Mar
4
2022

Department of Neuroscience Seminar Series: Robert C. Froemke, Ph.D. - "Neural circuits of oxytocin release for mouse maternal behavior"

When: Friday, March 4, 2022
12:00 PM - 1:00 PM Central

Where: Online
Webcast Link

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Emily Larsen   (312) 503-1687

Group: Department of Neuroscience Seminars

Category: Lectures & Meetings

Description:

Abstract:

Oxytocin is important for social interactions and maternal behavior. However, little is known about when, where, and how oxytocin modulates neural circuits to improve social cognition. Here I will discuss recent results and unpublished data from our lab on how oxytocin enables maternal behavior in new mother mice. I will focus on experience-dependent plasticity in auditory cortex related to recognizing the significance of pup distress calls, which are important for mother mice retrieving lost pups back to the nest. This behavior, neural responses, and oxytocin receptor expression were lateralized to the left side of female mouse auditory cortex, analogous to the left-hemisphere specialization for conspecific vocalizations observed in many other species. I will also describe a new system we have built to combine neural recordings from the auditory cortex and oxytocin neurons of the hypothalamus in vivo, synchronized with days-to-weeks long continuous video monitoring of homecage behavior to identify when oxytocin release and cortical plasticity might occur during natural social and maternal experience. This includes new data on how multimodal sensory inputs are routed to hypothalamic oxytocin neurons.

Join Zoom Meeting:

Meeting ID: 927 9216 2865 | Passcode: 529763

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