Northwestern Events Calendar

Jul
22
2022

Summer CDB "Scien-cial" Journal Club: Discovery of AUTACS, PROTACS, etc.

Purple background with yellow dna icons and blue and white cell and microscopes with text, "Join us for the Summer CDB "Scien-cial" Series; July 8, July 22, Aug 5, Aug 19, Sept 2; Social hour to follow"

When: Friday, July 22, 2022
3:30 PM - 5:30 PM CT

Where: Simpson Querrey Biomedical Research Center, Simpson Querrey Auditorium, SQBRC 1-230, 303 E. Superior Street, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Cell & Developmental Biology Department   (312) 503-7959

Group: Department of Cell and Developmental Biology

Category: Lectures & Meetings

Description:

Summer CDB "Scien-cial" Series

Journal Club Part 1: Discovery of AUTACS, PROTACS, etc.
Faculty-Led

Join us for our bi-weekly summer journal club and social events!

Friday, July 22nd
UPDATED LOCATION: SQ Auditorium, SQ 1-230

UPDATED TIMES: 
3:30-4:30pm: Journal Club

4:30-5:30pm: CDB Social Hour

Refreshments will be served

Articles to be discussed: 

Nishimura, K., Fukagawa, T., Takisawa, H., Kakimoto, T., and Kanemaki, M. 2009. An auxin-based degron system for the rapid depletion of proteins in nonplant cells. Nat Methods. 6(12):917-923. PMID: 19915560.

Sakamoto, K.M., Kim, K.B., Kumagai, A., Mercurio, F., Crews, C.M., and Deshaies, R.J. 2001. Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation. Proc Natl Acad Sci USA. 98(15):8554-8559. PMCID: PMC37474.

Lai, A.C., and Crews, C.M. 2017. Induced protein degradation: An emerging drug discovery paradigm. Nat Rev Drug Discov. 16(2):101-114. PMCID: PMC5684876.

Please contact cdb@northwestern.edu for additional information

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