When:
Monday, October 31, 2022
10:00 AM - 11:00 AM CT
Where: Robert H Lurie Medical Research Center, Searle Seminar Room, 303 E. Superior, Chicago, IL 60611 map it
Audience: Faculty/Staff - Post Docs/Docs - Graduate Students
Contact:
Cynthia Naugles
(312) 503-0489
Group: Department of Microbiology-Immunology
Category: Lectures & Meetings
Title:
Design, Validation, and Applications of a Synthetic Gut Microbiome
Speaker:
Alice Cheng, MD, PhD, Clinical Assistant Professor, Stanford University School of Medicine, Department of Gastroenterology & Hepatology
Topic:
Our research has focused on design and validation of the synthetic microbial community hCom2 as a model gut microbiome. hCom2 is comprised of 119 highly abundant and prevalent human gut strains, and largely recapitulates the phylogenetic diversity, complexity, stability, immune and metabolic functionality of native gut communities. To better understand the factors driving microbiota stability, we map and investigate hCom2 strain interactions and nutrient dependencies. We then demonstrate hCom2 as an experimental platform for investigation and treatment of microbiota-associated conditions such as enteropathogen infection and inflammatory colitis.
Host:
M.-N. Frances Yap, PhD
Associate Professor
Bacteriology Search Committee
Department of Microbiology-Immunology
Northwestern University Feinberg School of Medicine
Chicago, IL