Northwestern Events Calendar


M-I Dept. Bacteriology Faculty Candidate - Design, Validation, and Applications of a Synthetic Gut Microbiome

When: Monday, October 31, 2022
10:00 AM - 11:00 AM CT

Where: Robert H Lurie Medical Research Center, Searle Seminar Room, 303 E. Superior, Chicago, IL 60611 map it

Audience: Faculty/Staff - Post Docs/Docs - Graduate Students

Contact: Cynthia Naugles   (312) 503-0489

Group: Department of Microbiology-Immunology Seminars/Events

Category: Lectures & Meetings



Design, Validation, and Applications of a Synthetic Gut Microbiome


Alice Cheng, MD, PhD, Clinical Assistant Professor, Stanford University School of Medicine, Department of Gastroenterology &  Hepatology


Our research has focused on design and validation of the synthetic microbial community hCom2 as a model gut microbiome. hCom2 is comprised of 119 highly abundant and prevalent human gut strains, and largely recapitulates the phylogenetic diversity, complexity, stability, immune and metabolic functionality of native gut communities. To better understand the factors driving microbiota stability, we map and investigate hCom2 strain interactions and nutrient dependencies. We then demonstrate hCom2 as an experimental platform for investigation and treatment of microbiota-associated conditions such as enteropathogen infection and inflammatory colitis.


M.-N. Frances Yap, PhD

Associate Professor

Bacteriology Search Committee

Department of Microbiology-Immunology

Northwestern University Feinberg School of Medicine

Chicago, IL


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