Description:

** Please note the event runtime has been updated; See below for the detailed event schedule 

The end of the year is rapidly approaching and with it the passing of another year of progress in our research. Apkar V. Apkarian, PhD, director of the Center for Translational Pain Research, invites you for a day of celebration and annual review on December 6th. The day will consist of a series of talks led by students and lab members to fuel the process of discovery for the next year, as well a keynote seminar by Jelena Radulovic, MD, PhD, titled "The Neurobiology of Stress Related Memories." The annual review is a wonderful opportunity for labs to share research with one another and celebrate what we have all achieved.

This event will be in-person and on Zoom

Zoom Details: 
https://northwestern.zoom.us/j/93746952007?
Meeting ID: 937 4695 2007
Passcode: 319848

1:00 p.m. - 2:00 p.m. | Keynote Seminar: "The Neurobiology of Stress Related Memories"

Jelena Radulovic, MD, PhD
Professor, Dominick P. Purpura Department of Neuroscience 
Professor of Psychiatry and Behavioral Sciences
Director, Psychiatry Research Institute at Montefiore Einstein (PRIME)
Sylvia and Robert S. Olnick Chair in Neuroscience
Albert Einstein College of Medicine

Abstract: 

Our research focuses on the neurobiological mechanisms by which stressful experiences shape brain circuits and the representation of negative experiences. This presentation will summarize findings from selected translationally-relevant models of maladaptive behavioral phenotypes associated with stress-related memories and highlight newly identified, unexpected mechanisms contributing to the specificity and persistence of stress-related memories. These mechanisms highlight the role of ciliogenesis in integrating genomic responses of neurons to synaptic activity with the build-up of adjacent perineuronal nets.

**Schedule**

8:30 a.m. - Breakfast

9:00 a.m. - Welcoming Remarks - Apkar Vania Apkarian, PhD, Director, Center for Translational Pain Research

9:10 a.m. - 12:50 p.m. | Student Presentations

9:15 a.m. | μ - opioid receptor modulation of TH-Negative inputs from the VTA to the hippocampus dentate gyrus: properties and regulation by neuropathic pain" - Haram Kim, Martina Lab

9:30 a.m. | The MOR modulation of aversion-related circuits following fentanyl exposure and withdrawal - Yichen Wu, Surmeier Lab

9:55 a.m. | Core Circuit Dynamics during Aversive Learning - Gabriela Lopez, Lerner Lab

10:20 a.m. | Hippocampal maladaptive plasticity after injury predicts the development of chronic pain - Paulo Branco, Apkarian Lab

10:45 a.m. | Fentanyl Vapor Self-Administration in Mice with Chronic Pain - Sam Cermak, Apkarian Lab

11:10 a.m. | Behavioral and Brain Characteristic Associated with Long-term Opioid Exposure in Chronic Back Patients - Gaelle Rached, Apkarian Lab

11:35 p.m. | Molecular adaptations of VTA DA neurons during fentanyl consumption and withdrawal - Zack Gaertner, Awatramani Lab

Noon | Domains within the nucleus accumbens defined by projections of DA neuron subtypes - Oscar Ramos and Sage Morison, Awatramani Lab

1:00 p.m. | Keynote Seminar: “The Neurobiology of Stress Related Memories” - Jelena Radulovic, MD, PhD

2:00 p.m. | Lunch 

2:30 p.m.- 3:30 p.m. | Closed Leadership Discussion