When:
Monday, April 17, 2023
3:00 PM - 4:00 PM CT
Where: Ward Building, 5-230, 303 E. Chicago Avenue, Chicago, IL 60611 map it
Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students
Contact:
Melissa Daley
Group: Department of Pharmacology Seminars
Category: Lectures & Meetings
SCN2A related autism and epilepsy: from mouse and hiPSCs models to genetic medicine
Genetic mutation in SCN2A has been found to be the leading cause of monogenic autism and epilepsy. SCN2A encodes the voltage-gated sodium channel Nav1.2, a key mediator of neuronal action potential firing in the brain. In this lecture, Dr. Yang will discuss how SCN2A deficiency and genetic variants affect neuronal/circuit functions as well as animal behaviors in disease models. Dr. Yang will also discuss the development of potential genetic medicine for disease interventions of SCN2A-related disorders.
Yang Yang, PhD
Assistant Professor of Medicinal Chemistry and Molecular Pharmacology
Purdue University
Purdue | Y Lab | ResearchGate