Northwestern Events Calendar


BMG Seminar: Ekta Khurana, PhD, Weill Medical College of Cornell University, New York, NY

When: Thursday, January 12, 2023
10:00 AM - 11:00 AM CT

Where: Simpson Querrey Biomedical Research Center, Simpson Querrey Auditorium, 303 E. Superior Street, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Linda Mekhitarian Jackson   (312) 503-5229

Group: Biochemistry & Molecular Genetics Seminar Series

Category: Lectures & Meetings


The Department of Biochemistry & Molecular Genetics presents:

Ekta Khurana, PhD
Associate Professor of Computational Genomics
WorldQuant Foundation Research Scholar   
Co-leader of the Genetics and Epigenetics Program at Meyer Cancer Center 
Associate Director, Tri-Institutional PhD Program in Computational Biology and Medicine
Weill Medical College of Cornell University


"Cancer evolution through the lens of the non-coding genome"


After decades of research on understanding cancer growth and treatment resistance, numerous unanswered questions remain that constitute some of the biggest challenges in cancer research. I will discuss our approach to addressing these questions through the lens of the non-coding regulatory regions. I will discuss the novel computational methods we have developed to analyze whole-genome sequencing data and identify drivers of tumor growth. I will also discuss how generating a map of the regulatory regions in castration-resistant metastatic prostate cancer revealed dependencies that can be therapeutically targeted. Thus, the evolution of non-coding regions can reveal basic and translational insights about initial cancer growth and emergence of lineage plasticity in treatment resistant tumors.

Host: Dr. Feng Yue, Professor of Biochemistry and Molecular Genetics and Pathology

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