Northwestern Events Calendar


M-I Dept. Seminar Series /Gut IgA Beyond Microbes: How is IgA to Food Antigens Regulated?

When: Tuesday, February 7, 2023
12:00 PM - 1:00 PM CT

Where: Simpson Querrey Biomedical Research Center, SQ Auditorium, 303 E. Superior Street, Chicago, IL 60611 map it

Audience: Faculty/Staff - Post Docs/Docs - Graduate Students

Contact: Cynthia Naugles   (312) 503-0489

Group: Department of Microbiology-Immunology Seminars/Events

Category: Lectures & Meetings



Gut IgA Beyond Microbes: How is IgA to Food Antigens Regulated?


Stephanie C. Eisenbarth, MD, PhD

Northwestern University Feinberg School of Medicine 

Director, Center for Human Immunobiology 

Chief, Allergy & Immunology (Medicine)

Professor, Department of Pathology


Despite being the most abundant antibody isotype in the body, how IgA is induced to a wide variety of antigens at mucosal surfaces remains largely a mystery. IgA antibodies in the gut are thought to shape the microbiome, prevent infection with pathogens and neutralize toxins. We discovered that humans make gut IgA to food antigens as well; however, what this IgA does and how it is induced is not known. Our studies mouse and human studies focus on identifying the innate immune triggers inducing this T-dependent antibody response and discovering the physiologic role of food-specific IgA. 

Host: Laimonis Laimins, Professor and Chair, Dept. of Microbiology-Immunology





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