Title: B cells control and are controlled by infection-induced inflammation
Topic: This seminar will outline recent findings showing that B cells regulate respiratory tract macrophages via production of the neurotransmitter and immunomodulator acetyl choline, and discuss the impact this may have on immune imprinting in early life. Further, the talk will describe the effects of infection-induced inflammation on the quality and protective capacity of humoral immune responses, revealing a role for TLR3 signaling in B cell differentiation. Together, the seminar highlights the diverse functions of B cells and the complexity of signals that shape the humoral responses.
Speaker: Nicole Baumgarth, PhD, Johns Hopkins Bloomberg School of Public Health
Host: Bookie Min, PhD, Professor, Dept. of Microbiology-Immunology