Description:

Title: “Shaping of Immune Tolerance in the Periphery by Regulatory T cells”

Topic: This seminar describes my lab's investigation of T cell tolerance to self and commensal bacterial antigens.  I will focus on recent studies of peripheral regulatory T cell development in the context of acute injury in lung and gut tissues, and then transition into investigations of molecular mimicry as a mechanism of epitope spreading from microbial to self antigens in Lyme disease and rheumatoid arthritis.  These topics are of particular interest to immunologists and rheumatologists, but may also be of general interest to a broader audience including researchers in the fields of microbiology and infectious disease.

Speaker: James Moon, PhD, Assistant Professor, Harvard University

Host: Book Min, PhD, Professor, Dept. of Microbiology-Immunology