Description:

https://illinois.zoom.us/j/83039334291?pwd=FOmBWZeSwJfI1ac68Yd68QKSEYbtKj.1

Title: Disentangling Cellular Heterogeneities and Activities from the Topology Structures of Gene Co-expression Graphs 

Abstract: 

Gene co-expression graphs are a rich source of information, revealing critical insights into cellular functions, states, and activities. Yet, extracting meaningful signals from these graphs presents a formidable challenge. This complexity arises due to the presence of multiple, overlapping sources of heterogenous and cellular activity signals, and large inherent technical bias and noise in single-cell data. In this talk, we explore our latest endeavors and progress in unraveling these intricate signals in gene co-expression graphs. We focus on the identification and interpretation of various topological structures and demonstrate how these structures help in pinpointing feature genes and assessing cellular pathway activeness by further leveraging domain knowledge in online knowledge databases.

The Midwest Mathematical Biology Seminar will be a series of virtual talks on mathematical biology featuring speakers from the Midwest region and beyond. All areas of mathematical biology will be represented in the seminar series, and a goal for this seminar is to build connections and foster research collaborations.

More information - https://sites.google.com/view/midwest-mathbio-seminar/home