Description:

The Department of Biochemistry & Molecular Genetics presents:

Hui Shen, PhD
Professor
Department of Epigenetics
Van Andel Institute

Presentation:

"Cancer Epigenetics: From Genes to Cells”

Abstract:

Cancer arises as a result of cumulative genetic and epigenetic alterations in the genome. While the role of epigenetics in tumorigenesis is widely recognized, there remains debate about the precise definition and scope of epigenetics itself. In this seminar, I will explore these differing perspectives and present both wet-lab and computational approaches we have developed to investigate these epigenetic mechanisms in cancer and other settings. I will also discuss application of these and other tools to study tumorigenesis in the female reproductive system, in particular the origins of various ovarian cancer histotypes.

Host: Dr. Feng Yue, Professor of Biochemistry and Molecular Genetics, Pathology