Description:

Title: "AI-enabled design of novel self-assembling protein nanomaterials".

Abstract: New AI-based tools for protein design are revolutionizing the field. Dr. King will discuss how his group is applying these methods to design novel self-assembling proteins. Like naturally occurring protein assemblies, these materials provide unparalleled homogeneity, addressability, and functionality. However, unlike naturally occurring assemblies, protein design offers a route to tailoring the structure and function of self-assembling proteins with atomic-level accuracy. Dr. King will describe his group's current efforts in this space, which focus on developing methods to move beyond strict symmetry and design increasingly asymmetric and complex protein assemblies. Applications in nanoparticle vaccine design, including the development of the world's first computationally designed protein medicine, will be discussed.

Speaker: Neil King, PhD; Associate Professor of Biochemistry, University of Washington.