BEGIN:VCALENDAR
PRODID:-//planitpurple.northwestern.edu//iCalendar Event//EN
VERSION:2.0
CALSCALE:GREGORIAN
METHOD:PUBLISH
CLASS:PUBLIC
BEGIN:VTIMEZONE
TZID:America/Chicago
TZURL:http://tzurl.org/zoneinfo-outlook/America/Chicago
X-LIC-LOCATION:America/Chicago
BEGIN:DAYLIGHT
TZOFFSETFROM:-0600
TZOFFSETTO:-0500
TZNAME:CDT
DTSTART:19700308T020000
RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=2SU
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0500
TZOFFSETTO:-0600
TZNAME:CST
DTSTART:19701101T020000
RRULE:FREQ=YEARLY;BYMONTH=11;BYDAY=1SU
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
SEQUENCE:0
DTSTART;TZID=America/Chicago:20260618T090000
DTEND;TZID=America/Chicago:20260618T170000
DTSTAMP:20260514T055023Z
SUMMARY:Internal Conflicts and Organismal Adaptation: Mathematical Foundations
UID:630167@northwestern.edu
TZID:America/Chicago
DESCRIPTION: Organisms are held together by cooperation between their constituent parts: genes\, genomes\, and cells. This intimate integration underpins the complex adaptations that characterise plants\, fungi\, and animals. Like any collective\, however\, organisms are vulnerable to exploitation from within\, whether by selfish genetic elements enhancing their own transmission at the expense of other genes or selfish cell lineages\, such as cancerous tumours\, diverting resources away from the organismal optimum. Internal conflicts arise because different constituent parts experience optimal fitness under mutually exclusive conditions.   While the presence of within-organism conflicts is well-established empirically\, their implications for organismal biology are poorly worked out. The mathematical frameworks we currently use—including inclusive fitness\, game theory\, population and quantitative genetics—generally assume that organisms are coherent\, unified wholes\, and they brush aside the existence of internal conflicts. Whereas the mathematics of cooperation has developed alongside its empirical study and has given rise to a coherent framework for understanding cooperation in various contexts\, the mathematics of internal conflict has by and large lagged its empirical understanding and led to a proliferation of ad hoc models. Closing this knowledge gap requires developing a general mathematical framework that can make sense of organismal biology in the face of internal conflicts and meet the need for a formal theory of internal conflict.\n\nRegister: https://www.nitmb.org/internal-conflicts-workshop
LOCATION:Suite 3500\, Chicago\, IL 60615
TRANSP:OPAQUE
URL:https://planitpurple.northwestern.edu/event/630167
CREATED:20250708T050000Z
STATUS:CONFIRMED
LAST-MODIFIED:20250708T050000Z
PRIORITY:0
BEGIN:VALARM
TRIGGER:-PT10M
ACTION:DISPLAY
DESCRIPTION:Reminder
END:VALARM
END:VEVENT
END:VCALENDAR