Improved Animal Models for AIDS: Expanding HIV-1 Tropism: Theodora Hatziioannou, PhD

Microbiology-Immunology Seminar Series

Improved Animal Models for AIDS: Expanding HIV-1 Tropism

HIV-1, the predominant cause of AIDS in humans, is unable to replicate in most nonhuman primate species and current animal models are limited. By understanding the molecular mechanisms by which cellular proteins in different species limit virus replication we seek to generate novel viruses based on HIV-1 that can recapitulate the hallmarks of human disease in macaques. These new models will considerably facilitate the development and testing of drug and vaccine interventions.

Theodora Hatziioannou, PhD

Rockefeller University

Host: Eva Gottwein, PhD

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