The Department of Microbiology-Immunology Seminar Series
"Stenotrophomonas maltophilia Virulence: Siderophore Production and Type IV Secretion"
Megan Nas - Northwestern University, Driskill Gradute Program (DGP)
Description
Stenotrophomonas maltophilia, a gram negative multi drug resistant bacterium is increasingly being recognized as an important opportunistic and nosocomial pathogen. Despite the rise in incidence of S. maltophilia infection, there is very little known about its virulence. Exploring two facets of S. maltophilia virulence, siderophore production and type IV secretion, is critical to achieving full understanding of S. maltophilia pathogenesis and ultimately to developing antibiotic targets agains this infection of increasing significance. Pursing work on both virulence mechanisms can contribute to the characterization of novel factors in bacterial virulence, namely an unidentified siderophore and T4SS effector.
Dr. Nicholas Cianciotto
(312) 503-0385
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