Northwestern University

Feb
21
Thu 2:00 PM

SQE Invited Lecturer: Yamini Dalal, PhD

When: Thursday, February 21, 2019
2:00 PM - 3:00 PM  

Where: Robert H Lurie Medical Research Center, Baldwin Auditorium, 303 E. Superior, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Beverly Kirk   312.503.5217

Group: Simpson Querrey Center for Epigenetics Invited Lectureship

Category: Lectures & Meetings

Description:

The Simpson Querrey Center for Epigenetics presents:

Yamini Dalal, PhD
Senior Investigator, Receptor Biology and Gene Expression
Group Director, Chromatin Structure and Epigenetic Mechanisms Group
National Cancer Institute, Bethesda, MD

Title: Journey to the Black Hole of the Human Genome

Abstract: Unique chromatin structures dictate the functional fate of specific regions of the genome. Centromeres, encoded by the histone variant CENP-A, play an essential role in mitosis. In this lecture, I will discuss the naturally elastic nature of human centromeres, and discuss how such unique biophysical features can hijack non-centromere pathways to drive fragility at subtelomeric breakpoints in the cancer epigenome.

 

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