Northwestern University

Tue 12:00 PM

Microbiology-Immunology Department: Benjamin Gewurz, MD, PhD

When: Tuesday, November 13, 2018
12:00 PM - 1:00 PM  

Where: Robert H Lurie Medical Research Center, Hughes Auditorium, 303 E. Superior, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Dr. Eva Gottwein   312.503.3075

Group: Department of Microbiology-Immunology Seminars/Events

Category: Lectures & Meetings


Title: "CRISPR/Cas9 Genetic Analysis of the Epstein-Barr Virus Lifecycle

Benjamin Gewurz, MD, PhD

Harvard University

Hosts: Dr. Eva Gottwein and Richard Longnecker


 Epstein-Barr virus is associated with multiple human cancers, including lymphomas of immunosuppressed hosts, Burkitt and Hodgkin lymphoma, nasopharyngeal and gastric carcinomas. To gain insights into host factors that control key aspects of the EBV lifecycle, we are using CRISPR/Cas9 screens and temporal proteomic maps of viral latent and lytic infection states. This approach is highlighting vulnerabilities that may ultimately be exploited to selectively target EBV-infected cancers.

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