Northwestern University

Jan
15
Tue 12:00 PM

Microbiology-Immunology Department: Matthew Wargo, PhD

When: Tuesday, January 15, 2019
12:00 PM - 1:00 PM  

Where: Robert H Lurie Medical Research Center, Baldwin Auditorium, 303 E. Superior, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Dr. Alan Hauser   312.503.1044

Group: Department of Microbiology-Immunology Seminars/Events

Category: Lectures & Meetings

Description:

"Responses of Gram-Negative Lung Pathogens to the Host Environment"

Speaker: Matthew Wargo, University of Vermont

Host: Alan Hauser, MD, PhD

TOPIC

Many opportunistic Gram-negative pathogens make a transition from an environmental pre-infection niche into the lung where they can cause pneumonia or chronic infections in susceptible people. Initial detection of the host environment and elaboration of appropriate responses are required to initiate colonization and promote infection. We are examining the transcriptional and metabolic responses of Pseudomonas aeruginosa, Klebsiella pneumoniae, and Stenotrophomonas maltophilia to the lung environment and, for P. aeruginosa, contrasting the response to the lung with that to the pre-infection niche - potable water.

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