Northwestern University

Mar
5
Tue 12:00 PM

Microbiology-Immunology Department: Katherine A. Radek, PhD

When: Tuesday, March 5, 2019
12:00 PM - 1:00 PM  

Where: Robert H Lurie Medical Research Center, Baldwin Auditorium, 303 E. Superior, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Dr. Melissa Brown   312.503.0108

Group: Department of Microbiology-Immunology Seminars/Events

Category: Lectures & Meetings

Description:

"Cholinergic Regulation of Skin Antimicrobial Responses in Models of Injury and Infection"

Speaker: Katherine A. Radek, PhD - Loyola University Chicago

Host: Melissa Brown, PhD

TOPIC

The Radek laboratory focuses on how epidermal cholinergic signaling controls antimicrobial responses in the skin. The pathways by which skin antimicrobial responses are induced have been more thoroughly investigated, while those mechanisms which suppress them have not been fully elucidated. We established that activation of keratinocyte nicotinic acetylcholine receptors (nAChRs), specifically CHRNA7, dampens antimicrobial responses in several models of skin bacterial infection and wound healing. This suggests that CHRNA7 could be a novel target to boost skin antimicrobial responses as a means to improve infection and wound healing outcomes.

Add Event to Calendar

Add Event To My Group:

Please sign-in