Northwestern University

Tue 12:00 PM

Microbiology-Immunology Department: Lubov Grigoryeva

When: Tuesday, April 30, 2019
12:00 PM - 1:00 PM  

Where: Robert H Lurie Medical Research Center, Baldwin Auditorium, 303 E. Superior, Chicago, IL 60611 map it

Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students

Contact: Dr. Nicholas Cianciotto   312.503.0385

Group: Department of Microbiology-Immunology Seminars/Events

Category: Lectures & Meetings


"Endosomal TLRs are Major Pathways to Recognizing Legionella pneumophila in Human Macrophages"

Speaker: Lubov Grigoryeva, Driskill Graduate Program, Lab of Nicholas Cianciotto, PhD


Legionella pneumophila is a gram-negative bacterium that causes a severe form of pneumonia known as Legionnaire’s disease. Preliminary data from our laboratory revealed that the recognition of wild-type L. pneumophila by human macrophages deviates from previously reported pathways in murine macrophages, calling into question the field’s reliance on murine-based experimentation. My project seeks to understand the mechanisms of innate immune signaling in human macrophages after Lp infection.

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