When:
Tuesday, November 5, 2019
12:00 PM - 1:00 PM CT
Where: Simpson Querrey Biomedical Research Center, Auditorium, 303 E. Superior Street, Chicago, IL 60611 map it
Audience: Faculty/Staff - Post Docs/Docs - Graduate Students
Contact:
Dr. Karla Satchell
(312) 503-2162
Group: Department of Microbiology-Immunology Seminars/Events
Category: Lectures & Meetings
Title: Vibrio cholerae Responses to Antimicrobial Peptide Exposure
Speaker: Jyl Matson, PhD, University of Toledo
Host: Karla Satchell, PhD
Topic:
Vibrio cholerae, the causative agent of epidemic cholera, encounters a variety of stressful conditions in the human gastrointestinal tract and in the aquatic environment. One of the many stresses that the bacteria encounter in the host is exposure to antimicrobial peptides on mucosal surfaces. Our ongoing studies aim to characterize newly identified proteins and pathways that contribute to bacterial survival in the presence of antimicrobial peptide stress. Related to this work, we have also identified antimicrobial peptides as an inducer of virulence gene expression in V. cholerae. Therefore, we also aim to elucidate the exact mechanism by which this signal is sensed and used to modulate gene expression.