When:
Tuesday, January 28, 2020
12:00 PM - 1:00 PM CT
Where: Simpson Querrey Biomedical Research Center, SQBR Auditorium, 303 E. Superior Street, Chicago, IL 60611 map it
Audience: Faculty/Staff - Post Docs/Docs - Graduate Students
Contact:
Dr. Pablo Penaloza-MacMaster
(312) 503-5240
Group: Department of Microbiology-Immunology Seminars/Events
Category: Lectures & Meetings
Title: Gene and Viruses as Therapeutics for Cancer
Speaker: E. Antonio Chiocca, MD, PhD / Harvard University
Host: Pablo Penaloza-MacMaster, PhD
Topic:
Pathogens, such as viruses, can be turned into therapeutic modalities for a variety of diseases such as cancer, by genetic modification to turn them into gene therapy vectors or into cancer-selective infectious agents (oncolytic viruses). Glioblastoma is a deadly brain cancer. We have utilized gene therapy and oncolytic viral approaches to cause direct cytotoxicity and also stimulate immune responses against this cancer in mouse models and clinical trials in humans. I will discuss the biology of these approaches and the current state of clinical trials.