When:
Tuesday, February 18, 2020
12:00 PM - 1:00 PM CT
Where: Simpson Querrey Biomedical Research Center, SQBR Auditorium, 303 E. Superior Street, Chicago, IL 60611 map it
Audience: Faculty/Staff - Post Docs/Docs - Graduate Students
Contact:
Dr. Laiimonis Laimins
(312) 503-0648
Group: Department of Microbiology-Immunology Seminars/Events
Category: Lectures & Meetings
Title: Immediate Early Events of the HPV Life Cycle: Playing Hide and Seek with Host Defenses
Speaker: Martin Sapp, PhD / LSU Health
Host: Laimoinis Laimins, PhD
Topic:
Infection with high-risk HPV types is the cause for up to 5% of all human cancers, especially of the cervix, the oropharynx and the anogenital tract. I will be presenting our latest findings regarding the infectious entry and intracellular trafficking of HPV virions to establish infection using relevant cell culture models. Our findings suggest that HPV has evolved unique mechanisms to achieve infection without being sensed by host cell innate immune sensors.