Description:

Title: How Testosterone Shapes the T cell Response in Neuroinflammatory Disease

Speaker: Melissa Brown, PhD / Professor/ Northwestern University

Host: Laimonis Laimins, PhD

Topic:

It is well established that males are less susceptible to autoimmune disease than females.  Yet the underpinnings of this protection are still unclear.  I will discuss our recent studies aimed at understanding the role of the male sex hormone testosterone in altering autoreactive immune responses that drive neuroinflammation.  Understanding sex-biased immune responses is also likely to have important consequences for vaccine development and treatment of infection and cancer.