Title: Single Cell Virology (and Drug Repurposing Efforts Against SARS-CoV-2)
Speaker: Nir Drayman, PhD, Post-Doctoral Fellow, Pritzker School of Molecular Engineering, The University of Chicago
Host: Gregory A. Smith, PhD
Topic:
Single cell analyses have recently shown that virus-infected cells show extreme heterogeneity in the timing, level and final outcome of infection. In this seminar I will discuss recent work using HSV-1 as a model system to investigate viral infection as the single cell level. I will additionally discuss our recent drug repurposing efforts against SARS-CoV-2, leading to the identification of masitinib as a safe-in-humans, pan-corona and picorna- virusese inhibitor.