When:
Friday, February 18, 2022
12:00 PM - 1:00 PM CT
Where:
Online
Webcast Link
Audience: Faculty/Staff - Student - Post Docs/Docs - Graduate Students
Contact:
Emily Larsen
(312) 503-1687
Group: Department of Neuroscience Seminars
Category: Lectures & Meetings, Academic
Neural computations occurring simultaneously in multiple cerebral cortical regions are critical for mediating behaviors. Progress has been made in understanding how neural activity in specific cortical regions contributes to behavior. However, an understanding of how activity across multiple cortical regions coordinate unitary behavior is currently lacking. I this talk, I will present a suite of technologies to enable easy, robust access to much of the dorsal cortex of mice for optical and electrophysiological recordings. These include microsurgery robots that can programmed to perform delicate cranial microsurgical procedures in a semi-automated fashion; morphologically realistic, transparent polymer skulls that allow long-term (>300 days) optical access to much of the dorsal cortex for mesoscopic and cellular resolution imaging, and compatible miniaturized imaging devices (mini-mScope) that allow imaging cortex wide calcium activity in freely behaving mice. Finally, I will present preliminary findings from investigations using the mini-Scopes to study encoding of space in cortex-wide calcium dynamics in a spatial learning and navigation task.
Join Zoom Meeting
https://northwestern.zoom.us/j/93512834110?pwd=SkxHcG1yRGFOTnRZdllSRGxCdnZXUT09
Meeting ID: 935 1283 4110
Passcode: 397078