Northwestern Events Calendar


M-I Dept. Seminar Series - “Seeing the CNS Through The Eyes/Genetics Of HIV-1”

When: Tuesday, November 16, 2021
12:00 PM - 1:00 PM CT

Where: Simpson Querrey Biomedical Research Center, Auditorium, 303 E. Superior Street, Chicago, IL 60611 map it

Audience: Faculty/Staff - Post Docs/Docs - Graduate Students

Contact: Cynthia Naugles   (312) 503-0489

Group: Department of Microbiology-Immunology Seminars/Events

Category: Lectures & Meetings


Title: “Seeing the CNS Through The Eyes/Genetics Of HIV-1”

Ron Swanstrom, PhD

Department of Biochemistry & Biophysics, Dept. of Microbiology and Immunology,

University of North Carolina School of Medicine

Faculty Host: Mojgan Naghavi, PhD


HIV-1 can be found in CSF throughout viral infection raising the possibility of infection within the CNS. However, the CNS environment is very different compared to the lymphoid tissues that usually support viral replication. As a result of this difference the virus both undergoes a distinct evolutionary pathway to allow long term growth in resident CNS cells, and also has distinct interactions with inflammatory cells that migrate into the CNS. These unique interactions between HIV-1 and the CNS have implications for pathogenesis and for the latent reservoir.

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