Description:

Title:

Evolution-Proof Antibiotics: Can we make treatments that are both effective and evolutionarily robust?   

Speaker:

Samuel P. Brown, PhD

Professor, Biology, Georgia Tech
Director, Center for Microbial Dynamics and Infection (CMDI)

Topic:

Infection medicine currently faces two major and growing crises that impact the ability of MDs to treat bacterial infections with our current arsenal of antibiotics. The first is widely recognised – the evolution of antibiotic resistance. The second receives less attention – chronic polymicrobial infections where appropriate antibiotics often fail to resolve infections. I will discuss novel patient-specific control strategies that have the potential to effectively treat patients now and into the future. These diagnostic-conditional strategies are grounded in multi-scale modeling and experimentation, from within-host dynamics of multi-species infection microbiomes through to the epidemiological and evolutionary dynamics of competing pathogen strains.  

Host: Bacteriology Postdocs and Graduate Students

Coordinating Host:  Shantanu Shukla, PhD