Description:

Title:

The Epi-Omic’s of KSHV Gene Regulation

Speaker: John Karilojich, PhD, Associate Professor

Vanderbilt University Medical Center, Department of Pathology, Microbiology and Immunology                      

Topic:

My laboratory’s research program is currently focused on determining how viral infection intersects with host gene expression machineries. This includes investigating how gene regulatory processes serve as cell- Intrinsic barriers to infection as well as how viruses regulate gene expression programs. We primarily study these events using the human oncogenic gammaherpesvirus Kaposi’s sarcoma-associated herpesvirus (KSHV), which is a prominent cause of AIDS-associated cancers. At this seminar I will discuss our current findings pertaining to how epigenomic and epitranscriptomic marks influence the KSHV lifecycle.

Host: Eva Gottwein, PhD, Associate Professor, Dept. of Microbiology-Immunology