Northwestern Events Calendar


M-I Dept. Seminar/ Self-Nonself Discrimination Conferred by Regulatory T Cell Specificity

When: Tuesday, April 16, 2024
12:00 PM - 1:00 PM CT

Where: Simpson Querrey Biomedical Research Center, SQ Auditprium, 303 E. Superior Street, Chicago, IL 60611 map it

Audience: Faculty/Staff - Post Docs/Docs

Contact: Cynthia Naugles   (312) 503-0489

Group: Department of Microbiology-Immunology Seminars/Events

Category: Lectures & Meetings


Title:  Self-Nonself Discrimination  Conferred by Regulatory T Cell Specificity

Speaker: Peter Savage, PhD, Professor, Dept. of Pathology, The University of Chicago


During infection, in which both self- and pathogen-derived antigens are presented in an inflammatory environment permissive for T cell activation, how does the immune system selectively control self-reactive T cells while simultaneously enabling robust effector T cell responses to pathogen-derived antigens? In this study, we examine the hypothesis the regulatory T cells enforce this self-nonself discrimination by selectively constraining conventional T cells of shared specificity for the same self-peptide/MHC antigen.

Host: Booki Min, Phd, Professor, Dept. of Microbiology-Immunoloy

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