M-I Dept. Seminar / Visualizing Host-Virus Interactions at High Resolutions In Situ

Title: Visualizing Host-Virus Interactions at High Resolutions In Situ

Speaker:

Yong Xiong, PhD, Professor, Yale School of Medicine, Dept. of Molecular Biophysics and Biochemistry

Topic:

Obtaining comprehensive structural descriptions of viruses and macromolecules within the natural cellular context holds immense potential for understanding fundamental biology and improving health. Here, we present the recent advances in in situ single-particle cryo-electron microscopy (cryo-EM), which allows us to view how HIV-1 capsids interact with antiviral compounds within the actual environment of the virus, as well as providing a detailed view of protein synthesis within human cells.

Host: Mojgan Naghavi, PhD, Professor, Dept. of Microbiology-Immunology

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