Description:

Katherine Borden, PhD is being considered for the Breast Cancer Leadership position in the Robert H. Lurie Comprehensive Cancer Center. She will be presenting her work: 

"Cancer cells hijack RNA processing to transform cells inside and out" 

Abstract: Disruption of RNA processing occurs in cancers such as acute myeloid leukemia (AML). The eukaryotic translation initiation factor eIF4E provides a model to study how dysregulated RNA processing, RNA export and RNA translation can combinatorically drive oncogenic circuits in AML and other cancers. Targeting these pathways in AML resulted in remissions for some patients in clinical trials and provided a proof-of-principle that these pathways can be targeted and lead to clinical benefit.

Katherine Borden, PhD
Professor, Departments of Pathology and Cell Biology, Université de Montréal