Description:

Title: Thirty Years of STAT4 Play

Speaker: Mark Kaplan, PhD, Indiana University

Topic:

Signal Transducer and Activator of Transcription (STAT) proteins are critical mediators of cytokine-induced responses. STAT4, activated by IL-12, IL-23, and type I interferons, is required for the development of immunity to intracellular pathogens and type I inflammatory diseases. While we have a detailed understanding of how STAT4 promotes Th1 cells development, how STAT4 functions in other cell types is not well documented. This seminar will review STAT4 biology and present developing concepts for future study.

Host: M-I Dept. Immunology Postdocs and Graduate Students (Faculty: Booki Min, PhD)