Description:

Center for Catalysis and Surface Science (CCSS) Seminar Series

Thursday, May 22, 2025 | 11am-12pm CT
Ryan Hall, 4003 | 2190 Campus Drive (Virtual Option via Zoom)
Lunch provided

Join the Center for Catalysis and Surface Science (CCSS) for the Seminar Series. Hear from a postdoctoral scholar during a presentation. This month's speaker is Marvin Parasram.

About the Presentation

Speaker: Marvin Parasram

Title: "Anaerobic Heteroatom Transfer Reactions Promoted by Photoexcited 1,3-Dipoles"

Abstract:

Heteroatom units, such as carbonyls, alcohols, and amines, are prevalent motifs in many medicinally important compounds. Methods to incorporate these important functional groups at the expense of hydrocarbons rely on the use of non-commercial heteroatom transfer agents, precious transition metals, and/or costly engineered enzymes. Also, these methods often require exogenous oxidants to promote the C–heteroatom bonding event, which greatly limits substrate scope. Our laboratory focuses on the employment of economical 1,3-dipoles as versatile reagents that can serve as the hydrocarbon activator and the heteroatom atom source for the heteroatom incorporation of aliphatic systems under benign visible-light irradiation. Our contributions involve the cleavage of alkenes leading to valuable carbonyl derivatives and the direct C–H oxidation of hydrocarbons via anaerobic oxygen-atom transfer from photoexcited nitroarenes. Using photoexcited azoxys, an anaerobic nitrogen atom transfer event can occur leading to the aziridination of alkenes. Mechanistic studies reveal that the 1,3-dipoles are the sole photo-absorbing species, which leads to the formation of diradical intermediates that are responsible for heteroatom transfer events.

The mission of the Center for Catalysis and Surface Science (CCSS) is to promote interdisciplinary research fundamental to the discovery, synthesis, and understanding of catalysts and catalytic reactions essential to modern society. As a part of the Paula M. Trienens Institute for Sustainability and Energy, CCSS applies fundamental advances in catalysis science towards applications in alternative fuels, abatement of harmful emissions, resource recovery concepts, new processing routes, and many other strategies towards making chemicals more sustainable.