Title: The Role of Short and Long Noncoding RNAs in KSHV Biology
Description: Like all Herpesviruses, Kaposi’s Sarcoma-associated Herpesvirus (KSHV) encodes microRNAs and long noncoding RNAs. This seminar will discuss ribonomics approaches to determine miRNA targetomes and an example of how a single viral miRNA can contribute to tumorigenesis. One example of a viral noncoding RNA is the Antisense to LANA transcript (ALT) which targets host cellular splicing during lytic replication. Similar themes are currently under investigation for two additional g-herpesviruses- Epstein-Barr Virus and Murine gamma-herpesvirus 68.
Audience
- Faculty/Staff
- Student
- Post Docs/Docs
- Graduate Students
Contact
Amelia Crowe
Email
Interest
- Academic (general)