Learn how to work with Hi-C (high throughput chromosome conformation capture) data
Hi-C is a genome-wide assay used to measure the three-dimensional organization of chromatin by quantifying contact frequencies between genomic regions. This workshop will introduce the core steps of Hi-C data processing on Quest, including alignment, filtering, binning, and matrix normalization. We will also walk through common downstream analyses such as identifying A/B compartments, calling TADs, and detecting chromatin loops. Participants will run these steps on an example dataset and learn how key parameters influence resolution and data quality.
This workshop requires a laptop and basic familiarity with the command line (such as through prior attendance at the Command Line Introduction workshop).
Leticia Vega
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