Part of the Evolutionary Games: Mathematical Theory and Biological Insights workshop. All are welcome to attend this seminar.
Title: Mathematical modeling of spatial evolution with applications to biomedical systems
Abstract: Evolutionary dynamics permeates life and life-like systems. Mathematical methods can be used to study evolutionary processes, such as selection, mutation, and drift, and to make sense of many phenomena in life sciences. Mass-action (or mean-field) evolutionary dynamics have been studied over the last 100 years, and produced an enormous wealth of useful results. In this talk, however, I will discuss how spatial interactions may change the laws of evolution, giving rise to a number of interesting and counterintuitive findings. I will discuss both explicitly spatial systems and metapopulations, and demonstrate a number of scaling laws that describe production and spread of disadvantageous, neutral, and advantageous mutants. Applications of these laws to bacterial growth and carcinogenesis will be discussed.
The NSF-Simons National Institute for Theory and Mathematics in Biology Seminar Series brings together a mix of mathematicians and biologists to foster discussion and collaboration between the two fields. The seminar series typically takes place on Fridays from 10am - 11am at NITMB. Talks are in-person with the ability to join remotely.
Tiffany Leighton
Email